E-ISSN 2576-3288
 

Review Article 


Interaction of nanoparticles with central nervous system and its consequences

Sairanthry Suku Athira, Nadukkandy Prajitha, Parayanthala Valappil Mohanan*.

Abstract
Nanotechnology has gained non- replaceable role in a host of applications in biomedical, agricultural, consumer, military and in industrial sectors. However, when observed through the perspective of central nervous system particularly, studies evidently provide data on both beneficial and detrimental effects of nanoparticles. While there exist a milieu of beneficial applications like axonal regeneration, Central Nervous System (CNS) imaging, neurological surgeries etc., nanoparticles open the doorway for an array of toxic reactions in CNS centers because of their effortless passage through brain barriers.Even though literatures endow with generalized toxic mechanisms mediated by nanoparticles in varying tissues, specific toxic reactions in CNS are still lacking. Present review mainly focuses on different routes through which nanoparticles get access into the brain and certain modes of toxic mechanisms exhibited by nanoparticles in CNS. A number of applications of nanoparticles in the diagnosis and treatment of CNS disorders also will be reviewed in concise.

Key words: nanoparticles, blood brain barrier, nanotoxicity, cellular response, oxidative stress


 
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Pubmed Style

Athira SS, Prajitha N, Mohanan PV, . Interaction of nanoparticles with central nervous system and its consequences. Am J Res Med Sci. 2018; 4(1): 12-32. doi:10.5455/ajrms.20180717105137


Web Style

Athira SS, Prajitha N, Mohanan PV, . Interaction of nanoparticles with central nervous system and its consequences. http://www.ajrms.com/?mno=1105 [Access: December 09, 2018]. doi:10.5455/ajrms.20180717105137


AMA (American Medical Association) Style

Athira SS, Prajitha N, Mohanan PV, . Interaction of nanoparticles with central nervous system and its consequences. Am J Res Med Sci. 2018; 4(1): 12-32. doi:10.5455/ajrms.20180717105137



Vancouver/ICMJE Style

Athira SS, Prajitha N, Mohanan PV, . Interaction of nanoparticles with central nervous system and its consequences. Am J Res Med Sci. (2018), [cited December 09, 2018]; 4(1): 12-32. doi:10.5455/ajrms.20180717105137



Harvard Style

Athira, S. S., Prajitha, N., Mohanan, P. V. & (2018) Interaction of nanoparticles with central nervous system and its consequences. Am J Res Med Sci, 4 (1), 12-32. doi:10.5455/ajrms.20180717105137



Turabian Style

Athira, Sairanthry Suku, Nadukkandy Prajitha, Parayanthala Valappil Mohanan, and . 2018. Interaction of nanoparticles with central nervous system and its consequences. American Journal of Research in Medical Sciences, 4 (1), 12-32. doi:10.5455/ajrms.20180717105137



Chicago Style

Athira, Sairanthry Suku, Nadukkandy Prajitha, Parayanthala Valappil Mohanan, and . "Interaction of nanoparticles with central nervous system and its consequences." American Journal of Research in Medical Sciences 4 (2018), 12-32. doi:10.5455/ajrms.20180717105137



MLA (The Modern Language Association) Style

Athira, Sairanthry Suku, Nadukkandy Prajitha, Parayanthala Valappil Mohanan, and . "Interaction of nanoparticles with central nervous system and its consequences." American Journal of Research in Medical Sciences 4.1 (2018), 12-32. Print. doi:10.5455/ajrms.20180717105137



APA (American Psychological Association) Style

Athira, S. S., Prajitha, N., Mohanan, P. V. & (2018) Interaction of nanoparticles with central nervous system and its consequences. American Journal of Research in Medical Sciences, 4 (1), 12-32. doi:10.5455/ajrms.20180717105137





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