American Journal of Medical and Clinical Sciences. 2019; 4(1):(30-74)


Phytochemical screening and antimicrobial efficacy of the root bark of Securidaca longipedunculata extracts

Adekunle Odunayo Adejuwon, Victoria Anatolyivna Tsygankova, Abiola Muhammad Adeosun, Adefemi Olawale Falase, Olubunmi Sharon Obayemi, Fatai Ishola Amusa

Abstract

Background: In tropical Nigeria, plant parts are believed to possess phytochemicals that are capable of healing diverse ailments. 

Objective: Phytochemical screening and anti-bacterial efficacy of the root bark of Securidaca longipedunculata were evaluated in five different solvent extracts. 

Methods: Solvent extracts of the root bark of S. longipedunculata were prepared with hexane (HE), petroleum ether, methanol (ME), ethanol (ET), and water. Phytochemical screening was conducted on the extracts and the efficacies of the extracts were tested on Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas aeruginosa, and Candida albicans using agar well diffusion technique. 

Results: Phytochemical analysis of the root bark showed the presence of saponins, terpenoids, tannins, and alkaloids. It was observed that the HE extract of the root bark was effective on only K. pneumonia and P. aeruginosa at a minimum inhibitory concentration (MIC) of 133 mg/ml. The ET extract of the root bark was effective on P. aeruginosa and C. albicans at a MIC of 80 mg/ml. 

Conclusion: Phytochemical examination of the root bark of S. longipedunculata revealed the presence of some bioactive compounds. The HE and ET extracts produced considerable antimicrobial effects.

Most Viewed Article
  • The Community Home Model of Care – Household Based Community Embedded Dementia Care
    Dr. Rodney Jilek
    » Abstract » doi: 10.33425/2832-4226/22013

  • Impact of Gestational Period and Weight on Individual, Task and Environmental Constraints on Balance in Pregnant Women
    Abigayle E. Fontaine, Eryk P. Przysucha and Taryn Klarner
    » Abstract » doi: 10.33425/2832-4226/22012

  • The Effect of Fatigue on Flexion or Extension of Cervical Region in Participants with Myofascial Trigger Point in Upper Trapezius Muscle
    Roya Mehdikhani, Gholam Reza Olyaei, Mohammad Reza Hadian, Saeed Talebian Moghaddam, Azadeh Shadmehr
    » Abstract » doi: 10.33425/2832-4226/22012

  • Xanthogranulomatous Pyelonephritis, a Great Imitator: Case Report
    Adolfo Boada, Stephanie Plaza and Renzo Nervi
    » Abstract » doi: 10.33425/2832-4226/22011

  • Understanding the Distinctions of Positive Constructs Resilience, Grit and Hardiness
    Vasiliki Georgoulas-Sherry PhD
    » Abstract » doi: 10.33425/2832-4226/22007

Most Downloaded
  • The Community Home Model of Care – Household Based Community Embedded Dementia Care
    Dr. Rodney Jilek
    » Abstract » doi: 10.33425/2832-4226/22013

  • Impact of Gestational Period and Weight on Individual, Task and Environmental Constraints on Balance in Pregnant Women
    Abigayle E. Fontaine, Eryk P. Przysucha and Taryn Klarner
    » Abstract » doi: 10.33425/2832-4226/22012

  • The Effect of Fatigue on Flexion or Extension of Cervical Region in Participants with Myofascial Trigger Point in Upper Trapezius Muscle
    Roya Mehdikhani, Gholam Reza Olyaei, Mohammad Reza Hadian, Saeed Talebian Moghaddam, Azadeh Shadmehr
    » Abstract » doi: 10.33425/2832-4226/22012

  • Xanthogranulomatous Pyelonephritis, a Great Imitator: Case Report
    Adolfo Boada, Stephanie Plaza and Renzo Nervi
    » Abstract » doi: 10.33425/2832-4226/22011

  • Understanding the Distinctions of Positive Constructs Resilience, Grit and Hardiness
    Vasiliki Georgoulas-Sherry PhD
    » Abstract » doi: 10.33425/2832-4226/22007