Primary Intracranial Myxoid Chondrosarcoma: A case report
Hayam E. Rashed, Aziza E. Abdelrahman, Wael Elmesallamy, Ahmed A. E. Obaya
Objective: Intracranial extraskeletal myxoid chondrosarcoma is a very rare tumor; up to
date, only ten cases have been reported.
Case report: We present a case report of a 65-year-old female admitted to Zagazig university
hospitals by right side hemiplegia of gradual onset and progressive course over
three weeks. Magnetic resonance imaging (MRI) revealed left intra-axial parieto-occipital
space occupying lesion, multiloculated, hypodense with central necrosis, heterogeneous
enhancement, minimal brain edema, and causing a mass effect. The patient underwent
subtotal resection using sonar guided craniotomy. The histopathological and immunohistochemical
evaluation confirmed a diagnosis of extraskeletal myxoid chondrosarcoma.
One month after initial discharge, the patient underwent radiotherapy. About 6 months
after surgery, the patient was deteriorated and died.
Conclusion: Intracranial extraskeletal myxoid chondrosarcoma is a rare malignant cartilaginous tumor. Pathological diagnosis is the gold standard and radical excision is the standard treatment.