E-ISSN 2576-3288


American Journal of Research in Medical Sciences. 2018; 3(1):(18-49)


An in vitro screening study of food functions among vegetable cultivars consumed in Japan

Naoki Ohkura, Riko Fujita, Ruri Kanai, Kenichi Ishibashi, Hiroshi Ueda, Gen-ichi Atsumi

Abstract

Aim: Ingesting vegetables plays a major role in health maintenance and disease prevention. Therefore, this study aimed to identify hitherto unknown food functionalities among various vegetable cultivars consumed in Japan. 

Methods: Water-soluble vegetable extracts were screened for various types of functionality such as antioxidant action, the inhibition of platelet aggregation, blood coagulation, and the enzymatic actions of α-glucosidase and pancreatic lipase. Antioxidant activity was measured as the ability to scavenge 1,1-diphenyl-2-picrylhydrazine (DPPH) radicals and the inhibitory activity of rat intestinal α-glucosidase was evaluated by measuring amounts of glucose produced from maltose. Lipase activities were measured using porcine pancreatic lipase and synthetic substrate. Platelet aggregation was measured using bovine whole blood stimulated with collagen. Plasma coagulation activities were measured using human plasma. Coagulation was initiated using intrinsic and extrinsic coagulation initiators and coagulation times were measured using a coagulometer. 

Results: All extracts from cabbage, onion, eggplant, tomato, green pepper, Japanese radish, and Chinese cabbage and their cultivars exerted antioxidant activities. All vegetable extracts had weak α-glucosidase inhibitory activity, but one Chinese cabbage cultivar had significantly more of such activity. All vegetable extracts had very weak ability to inhibit pancreatic lipase and did not inhibit platelet aggregation or affect intrinsic and extrinsic blood coagulation activity. 

Conclusion: Although further investigations are needed, the present findings provide fundamental information about the functionality of some vegetables consumed in Japan.

Most Viewed Article
  • High Medical Risk and Low Criminogenic Risk: What is the Price?
    Vasiliki Georgoulas-Sherry and Hanna G. Hernandez
    » Abstract » doi: 10.5455/ajrms:xxxxxxxxxxxxxx

  • Investigating the Link between Irregular Muscle Tension and Bodily Fatigue among High- Speed String Instrument Musicians
    Hiroshi Tanabe, Hirofumi Tanabe, Toshimasa Mikawa and Yuichi Takata
    » Abstract » doi: 10.5455/ajrms:xxxxxxxxxxxxxx

  • A Risk Score Proposal for Covid-19 in Nursing Homes
    Ambra Raimondi MD, Gianluigi Poma MD, Domenico Zanaboni MD, Carolina Dellafiore MD, Elisabetta Above MD, Andrea Agostinelli MD, Catherine Klersy MD, Virginia Valeria Ferretti PhD, Anna Maria Grugnetti PhD, Andrea Falconeri MD, Vittoria Infantino MD, Lorena Sega MD, Valeria Meroni PhD, Antonio Piralla PhD, Fausto Baldanti MD and Carlo Filice MD
    » Abstract » doi: 10.5455/ajrms:xxxxxxxxxxxxxx

  • WISQ (Women in Surgery Questionnaire): A Glimpse at the Caribbean Perspective
    Calderon C, Maraj A, Roopnarine C and Crichlow J
    » Abstract » doi: 10.5455/ajrms:xxxxxxxxxxxxxx

  • Risk of malnutrition in pulmonary fibrosis outpatients
    Botilla Dalsgaard Jensen (BJ) Stud. MSc, Sabina Mikkelsen (SM), MSc, Pernille Høyrup Krogh (PK) Stud. MSc, Christina Hornskov Lyngholm (CL) Stud. MSc, Jasmina Huremovic (JH), Consultant, MD and Mette Holst (MH), MCN, Ph.D
    » Abstract » doi: 10.5455/ajrms:xxxxxxxxxxxxxx

Most Downloaded
  • High Medical Risk and Low Criminogenic Risk: What is the Price?
    Vasiliki Georgoulas-Sherry and Hanna G. Hernandez
    » Abstract » doi: 10.5455/ajrms:xxxxxxxxxxxxxx

  • Investigating the Link between Irregular Muscle Tension and Bodily Fatigue among High- Speed String Instrument Musicians
    Hiroshi Tanabe, Hirofumi Tanabe, Toshimasa Mikawa and Yuichi Takata
    » Abstract » doi: 10.5455/ajrms:xxxxxxxxxxxxxx

  • A Risk Score Proposal for Covid-19 in Nursing Homes
    Ambra Raimondi MD, Gianluigi Poma MD, Domenico Zanaboni MD, Carolina Dellafiore MD, Elisabetta Above MD, Andrea Agostinelli MD, Catherine Klersy MD, Virginia Valeria Ferretti PhD, Anna Maria Grugnetti PhD, Andrea Falconeri MD, Vittoria Infantino MD, Lorena Sega MD, Valeria Meroni PhD, Antonio Piralla PhD, Fausto Baldanti MD and Carlo Filice MD
    » Abstract » doi: 10.5455/ajrms:xxxxxxxxxxxxxx

  • WISQ (Women in Surgery Questionnaire): A Glimpse at the Caribbean Perspective
    Calderon C, Maraj A, Roopnarine C and Crichlow J
    » Abstract » doi: 10.5455/ajrms:xxxxxxxxxxxxxx

  • Risk of malnutrition in pulmonary fibrosis outpatients
    Botilla Dalsgaard Jensen (BJ) Stud. MSc, Sabina Mikkelsen (SM), MSc, Pernille Høyrup Krogh (PK) Stud. MSc, Christina Hornskov Lyngholm (CL) Stud. MSc, Jasmina Huremovic (JH), Consultant, MD and Mette Holst (MH), MCN, Ph.D
    » Abstract » doi: 10.5455/ajrms:xxxxxxxxxxxxxx