Peer-reviewed medical journal Vol. 11 • Issue 1

Open access scholarly publishing

American Journal of Medical and Clinical Sciences

A clean, publisher-style platform for clinical science, evidence summaries, and online-first research dissemination.

Open Access Peer Reviewed Rapid Online First

Current publishing cycle

Volume 11

Issue 1 • 2026-02

1.387 Impact factor
Open Access model

Article details

Explosive onset of SLE in white male in capital of Cherokee Nation

Caleb S. Alexander, Prashant Kaushik.

Abstract

Systemic lupus erythematosus (SLE) is a major autoimmune rheumatologic condition that can cause severe life threatening complications. While it afflicts all ages, sexes, races and ethnicities, it overwhelmingly affects more females and non-white males. Due to these demographics, it is important to highlight this case of an explosive onset of SLE in a young, white male from a unique location in the USA. A 19-year old, white male first had symptoms following a change to carnivore diet, increase in exercise and prolonged sun exposure. Over the first few months, a rash that had started on his face and was originally thought to be a sunburn spread across the majority of his body. He then developed ascending joint pains and a loss of appetite. Over the course of about 6 months, he had gone from a relatively healthy, but overweight, teenager to requiring hospitalization for severe body pains and rash, photophobia, hyperacusis, lack of an appetite and nearly 30-percent loss of body weight loss. Since disease identification and receiving treatment, the symptoms have begun improving and he is resuming normal daily activities.