Peer-reviewed medical journal Vol. 11 • Issue 1

Open access scholarly publishing

American Journal of Medical and Clinical Sciences

A clean, publisher-style platform for clinical science, evidence summaries, and online-first research dissemination.

Open Access Peer Reviewed Rapid Online First

Current publishing cycle

Volume 11

Issue 1 • 2026-02

1.387 Impact factor
Open Access model

Article details

Oxidative stress in relation to chronic periodontal disease

Kluknavská Janka, Timková Silvia, Schwartzová Vladimíra, Vašková Janka

Abstract

Chronic periodontal disease is a relatively common inflammatory disease which, untreated, can lead to premature tooth loss. Many factors, including oxidative stress, play a role in the etiology of this disease. Various markers of oxidative stress have been evaluated in saliva and sulcular fluid between patients with chronic periodontal disease and healthy people in many studies, with some current studies suggesting changes in both the local and systemic redox equilibrium of patients. Antioxidant therapy seems to have its place in the therapeutic options for patients with gingivitis and periodontal disease. There has been evidence of positive effects in treatment with antioxidants along with scaling and root planning.
In the future, we anticipate that the determination of the selected antioxidant markers could be helpful in the diagnosis of chronic periodontal disease or evaluating therapy.