American Journal of Medical and Clinical Sciences. 2019; 4(1):(31-74)


Oxidative stress in relation to chronic periodontal disease

Kluknavská Janka, Timková Silvia, Schwartzová Vladimíra, Vašková Janka

Abstract
Chronic periodontal disease is a relatively common inflammatory disease which, untreated, can lead to premature tooth loss. Many factors, including oxidative stress, play a role in the etiology of this disease. Various markers of oxidative stress have been evaluated in saliva and sulcular fluid between patients with chronic periodontal disease and healthy people in many studies, with some current studies suggesting changes in both the local and systemic redox equilibrium of patients. Antioxidant therapy seems to have its place in the therapeutic options for patients with gingivitis and periodontal disease. There has been evidence of positive effects in treatment with antioxidants along with scaling and root planning.
In the future, we anticipate that the determination of the selected antioxidant markers could be helpful in the diagnosis of chronic periodontal disease or evaluating therapy.
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